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Zoledronic Acid Infusion in Edmonton
Zoledronic acid infusion is an IV bone medicine that slows bone loss. Doctors prescribe it for osteoporosis and Paget's disease of bone. It is usually given once a year through a vein over at least 15 minutes. Solis Medical Clinic in Edmonton gives zoledronic acid infusions with a prescription from your physician or nurse practitioner.

Why Choose Solis for Zoledronic Acid Infusions?
Comfort & Calm
An infusion space designed to promote relaxation and reduce anxiety.
Expert Team
Onsite Anesthesiologist and Registered Nurses, ACLS and BLS certified.
Emergency Ready
Fully equipped to handle unexpected emergencies, with safety first.
Insurance Help
Medication is usually covered by health care benefits, and we can help you get insurance approval.
What is zoledronic acid infusion used for?
Zoledronic acid is a bisphosphonate. It works by slowing the cells that break down bone. The benefit is slower bone loss and stronger bones, which can lower the chance of a fracture. It is used for:
- Osteoporosis after menopause
- Osteoporosis in men
- Osteoporosis caused by long-term steroid medicine
- Paget's disease of bone
How is a zoledronic acid infusion given?
A nurse places a small IV in your arm. The medicine runs slowly for at least 15 minutes. At Solis, please be prepared to be here for longer than 45 minutes, up to 2 hours, including checks and monitoring.
For osteoporosis, IV zoledronic acid infusion is usually given once a year. For Paget's disease, it is often a single dose. Your prescription sets the dose and schedule.
How to prepare for a zoledronic acid infusion
A few simple steps lower the risk of side effects. These follow Health Canada's drug information for zoledronic acid.
- Eat normally and drink at least 2 cups (500 mL) of fluid before and after
- Take calcium and vitamin D as your prescriber advises
- Get your kidney and calcium bloodwork done first
- Tell us about dental problems or planned dental work
What are the side effects of zoledronic acid infusion?
The most common after effects are flu-like: fever, chills, headache, tiredness and muscle, bone or joint aches. They are most common after the first dose and usually pass within a few days. Rest and fluids help. Ask your prescriber which pain medicine is safe for you.
Rare but serious effects need a call to your doctor. Call 911 for trouble breathing or swelling of the face, lips or throat.
- Jaw pain, swelling or a loose tooth
- New thigh, hip or groin pain
- Eye pain, redness or vision changes
- Passing less urine, or muscle spasms and tingling around the mouth
Visit the West Edmonton clinic
Solis is on 118 Avenue in West Edmonton. Call before you travel, whether you live in Edmonton or the surrounding areas, so staff can confirm that your prescription, bloodwork and coverage are ready.
Frequently asked questions
How long does a zoledronic acid infusion take?
The medicine runs for at least 15 minutes. With checks and monitoring, plan to be at Solis for longer than 45 minutes, up to 2 hours.
How many zoledronic acid infusions can you have?
For osteoporosis, most people get one infusion a year. Your prescriber checks your bone density over time and decides how long to continue or when to take a break.
Can you drink alcohol after a zoledronic acid infusion?
There is no specific ban, but alcohol can dehydrate you, and fluids protect your kidneys on infusion day. Skip it that day, keep drinking water, and tell your prescriber how much you usually drink.
Can you drive after a zoledronic acid infusion?
Most people can drive home. Do not drive if you feel dizzy, weak or unwell after the infusion.
Does zoledronic acid affect the immune system?
It does not weaken your immune system. The flu-like symptoms after a first dose are a short immune reaction that usually passes in a few days.
Who should not have a zoledronic acid infusion?
It is not used during pregnancy or breastfeeding, with severe kidney disease, with low blood calcium that has not been corrected, with an allergy to bisphosphonates, or in anyone under 18.
Can I have dental work after a zoledronic acid infusion?
Tell your dentist you receive zoledronic acid. Talk to your dentist and prescriber before a tooth extraction or implant, and report jaw pain, swelling or a loose tooth.
Do I need a prescription, and what does it cost?
Yes, a prescription is necessary. Your physician or nurse practitioner can fax it to us, and forms are on our referral page. There is an administration fee, currently $115, which does not include the medication. The medication is usually covered by your health care benefits, and we can help you get insurance approval.
Related care and patient guides
Send a zoledronic acid referral
Ask your physician or nurse practitioner to fax the prescription. We contact you within 24 to 48 hours to book.
Call to BookPhysician Referral